Gurmit Singh Selected Research

Antiporters

5/2019	Spinal microglia contribute to cancer-induced pain through system xC --mediated glutamate release.
1/2019	Inhibiting STAT3 in a murine model of human breast cancer-induced bone pain delays the onset of nociception.
1/2018	Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain.
1/2017	Identification of capsazepine as a novel inhibitor of system xc- and cancer-induced bone pain.
1/2017	Tumour-Derived Glutamate: Linking Aberrant Cancer Cell Metabolism to Peripheral Sensory Pain Pathways.
1/2016	Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity.
8/2015	Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
7/2015	Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells.
1/2014	Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain.
1/2013	Oxidative stress and cancer pain.

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Gurmit Singh Research Topics

Disease

60	Neoplasms (Cancer) 02/2020 - 03/2002
23	Breast Neoplasms (Breast Cancer) 01/2020 - 03/2002
16	Neoplasm Metastasis (Metastasis) 01/2019 - 03/2002
15	Pain (Aches) 01/2020 - 11/2010
11	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 05/2003
9	Carcinoma (Carcinomatosis) 05/2019 - 03/2005
5	Cancer Pain 02/2020 - 01/2014
5	Giant Cell Tumor of Bone 06/2012 - 01/2009
5	Bone Resorption 03/2012 - 03/2002
4	Neuralgia (Stump Neuralgia) 02/2020 - 01/2018
3	Necrosis 03/2021 - 10/2002
3	Glioma (Gliomas) 11/2015 - 01/2010
3	Adenocarcinoma 01/2014 - 01/2005
3	Ovarian Neoplasms (Ovarian Cancer) 11/2013 - 10/2010
3	Lung Neoplasms (Lung Cancer) 05/2012 - 07/2008
2	COVID-19 03/2021 - 01/2021
2	Infections 03/2021 - 10/2003
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 11/2015
2	Arthritis (Polyarthritis) 01/2020 - 07/2007
2	Intractable Pain 01/2019 - 01/2014
2	Inflammation (Inflammations) 01/2018 - 07/2007
2	Anhedonia 01/2017 - 11/2015
2	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2014 - 09/2010
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2009 - 07/2008
2	Li-Fraumeni Syndrome 10/2003 - 10/2002
1	Chronic Pain 11/2020
1	Hypersensitivity (Allergy) 01/2020
1	Bone Neoplasms (Bone Cancer) 01/2020
1	Synovial Cyst 12/2019

Drug/Important Bio-Agent (IBA)

23	Glutamic Acid (Glutamate)FDA Link 03/2021 - 01/2009
11	AntiportersIBA 05/2019 - 01/2010
11	Proteins (Proteins, Gene)FDA Link 05/2019 - 10/2002
9	Cystine (L-Cystine)IBA 01/2019 - 01/2010
9	EnzymesIBA 01/2019 - 11/2003
7	Reactive Oxygen Species (Oxygen Radicals)IBA 08/2015 - 12/2005
7	Matrix Metalloproteinases (MMPs)IBA 03/2012 - 03/2002
6	Messenger RNA (mRNA)IBA 01/2019 - 10/2007
6	AntioxidantsIBA 01/2019 - 10/2007
6	Phosphotransferases (Kinase)IBA 06/2014 - 07/2008
6	AndrogensIBA 10/2010 - 05/2003
6	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2010 - 10/2002
5	CytokinesIBA 01/2020 - 08/2009
5	Transcription Factors (Transcription Factor)IBA 05/2019 - 04/2002
5	AMP-Activated Protein KinasesIBA 02/2014 - 09/2010
4	Biological ProductsIBA 11/2020 - 01/2010
4	Glutathione (Reduced Glutathione)IBA 01/2019 - 03/2010
4	Tetracycline (Achromycin)FDA LinkGeneric 11/2013 - 03/2002
4	Fatty Acids (Saturated Fatty Acids)IBA 02/2011 - 09/2007
3	Biomarkers (Surrogate Marker)IBA 03/2021 - 01/2016
3	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2017 - 11/2013
3	Neurotransmitter Agents (Neurotransmitter)IBA 11/2015 - 01/2013
3	Glycerolphosphate Dehydrogenase (Glycerol 3 Phosphate Dehydrogenase)IBA 02/2014 - 08/2005
3	Parathyroid Hormone-Related ProteinIBA 06/2012 - 01/2011
3	Doxycycline (Periostat)FDA LinkGeneric 02/2009 - 03/2002
3	Dihematoporphyrin Ether (Porfimer Sodium)FDA Link 01/2009 - 10/2002
2	CannabinoidsIBA 03/2021 - 01/2020
2	InterleukinsIBA 03/2021 - 01/2003
2	ChemokinesIBA 01/2020 - 01/2003
2	Diphosphonates (Bisphosphonates)IBA 01/2020 - 05/2009
2	Analgesics (Analgesic Drugs)IBA 01/2020 - 01/2017
2	Nerve Growth Factor (NGF)IBA 01/2019 - 01/2018
2	Small Interfering RNA (siRNA)IBA 01/2019 - 02/2011
2	GlutaminaseIBA 01/2019 - 01/2017
2	RNA (Ribonucleic Acid)IBA 01/2019 - 01/2010
2	Glutamine (L-Glutamine)FDA Link 01/2019 - 01/2017
2	Sucrose (Saccharose)IBA 01/2017 - 11/2015
2	ProlactinIBA 06/2014 - 02/2011
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 02/2014 - 12/2005
2	Pharmaceutical PreparationsIBA 11/2013 - 02/2009
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2010 - 01/2003
2	Amino Acids FDA Link 03/2010 - 01/2010
2	Proto-Oncogene Protein c-ets-1IBA 03/2010 - 12/2005
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2009 - 01/2006
2	Cisplatin (Platino)FDA LinkGeneric 02/2009 - 07/2004
2	matrigelIBA 07/2008 - 07/2007
2	Insulin-Like Growth Factor I (IGF-1)IBA 07/2008 - 01/2003
2	estropipate (Ogen)FDA LinkGeneric 01/2006 - 04/2004
2	FibrinIBA 01/2006 - 04/2004
2	PlasminogenIBA 01/2006 - 05/2002
2	Photosensitizing Agents (Photosensitizers)IBA 03/2005 - 10/2002
2	Conditioned Culture MediaIBA 01/2005 - 01/2003
1	CannabidiolIBA 03/2021
1	C-Reactive ProteinIBA 03/2021
1	VaccinesIBA 03/2021
1	InterferonsIBA 03/2021
1	fibrin fragment D (D-dimer)IBA 03/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021
1	lopinavir-ritonavir drug combination (Kaletra)FDA Link 01/2021
1	Ritonavir (Norvir)FDA Link 01/2021
1	Lopinavir FDA Link 01/2021
1	Progesterone FDA LinkGeneric 02/2020
1	Pregabalin (Lyrica)FDA Link 02/2020
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020
1	EstersIBA 01/2020
1	Opioid Analgesics (Opioids)IBA 01/2020
1	cannabidiolic acidIBA 01/2020

Therapy/Procedure

15	Therapeutics 03/2021 - 10/2002
4	Photochemotherapy (Photodynamic Therapy) 01/2009 - 10/2002
3	Drug Therapy (Chemotherapy) 01/2020 - 07/2008
3	Radiotherapy 10/2011 - 01/2007